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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAP3K14 All Species: 8.18
Human Site: S758 Identified Species: 30
UniProt: Q99558 Number Species: 6
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99558 NP_003945.2 947 104042 S758 A P A R N P S S P E R K A T V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001115538 947 104061 S758 A P A R N P S S P E R K A T F
Dog Lupus familis XP_548049 955 104667 S766 T P A K N P S S A E R K A T L
Cat Felis silvestris
Mouse Mus musculus Q9WUL6 942 103061 F753 A T A K G P S F P D R R A T L
Rat Rattus norvegicus NP_001101771 942 103566 L753 A P A K G P S L P D R R A T F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515861 418 45090 P242 W R G E Y R E P R R L A V N A
Chicken Gallus gallus NP_001026098 909 100834 R733 N A S R E L S R I W D P P P L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.1 88.6 N.A. 84.4 85.2 N.A. 32.3 58.7 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 98.6 92.7 N.A. 90 90.3 N.A. 36.4 70 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 93.3 73.3 N.A. 53.3 60 N.A. 0 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 93.3 86.6 N.A. 80 80 N.A. 0 26.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 58 15 72 0 0 0 0 0 15 0 0 15 72 0 15 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 29 15 0 0 0 0 % D
% Glu: 0 0 0 15 15 0 15 0 0 43 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 15 0 0 0 0 0 0 29 % F
% Gly: 0 0 15 0 29 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % I
% Lys: 0 0 0 43 0 0 0 0 0 0 0 43 0 0 0 % K
% Leu: 0 0 0 0 0 15 0 15 0 0 15 0 0 0 43 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 15 0 0 0 43 0 0 0 0 0 0 0 0 15 0 % N
% Pro: 0 58 0 0 0 72 0 15 58 0 0 15 15 15 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 15 0 43 0 15 0 15 15 15 72 29 0 0 0 % R
% Ser: 0 0 15 0 0 0 86 43 0 0 0 0 0 0 0 % S
% Thr: 15 15 0 0 0 0 0 0 0 0 0 0 0 72 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 15 % V
% Trp: 15 0 0 0 0 0 0 0 0 15 0 0 0 0 0 % W
% Tyr: 0 0 0 0 15 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _